Dr. Sheng Feng got his PhD in statistical genetics. He became a Professor of Biostatistics and Bioinformatics in the Washington University at St. Louis and the Duke University, before moving to pharmaceutical industry. He has led several large-scale projects on BIG DATA and precision medicine, with a focus on their implementation in clinical trials. Combing both public big data and specific subject-matter knowledge, Dr. Feng was able to show that, BIG DATA, machine learning and precision medicine could be real for “real-world” clinical trials.